Abstract: To address the limitations in current human-land relationship research, including the lack of spatial information and overly coarse research scales, it takes Kaifeng City as the research object, with townships and subdistricts as the basic analytical units. Based on multi-source data, it integrates the geographic concentration index, allometric growth model, and coupling coordination degree model to systematically analyze the coupling and coordinated development relationship of the population system and the construction land system of Kaifeng City. The key findings are as follows: Total population growth coexists with spatial distribution imbalance; The geographic concentration of the population presents a concentric structure of "dense in the central urban area and sparse in the periphery", while regional development patterns show a dual trend of "Flattening" and "Three-dimensionalization"; The human-land growth relationship in Kaifeng City as a whole and its urban districts tends to be proportional and coordinated, but there are significant disparities among different districts and counties; The overall human-land coupling degree is relatively high but shows a downward trend, and most regions remain in the high-level coupling stage, while areas in the adjustment stage exhibit an expanding trend; The human-land coordination degree continues to decline, with the coordination type evolving toward high-level disharmony.