Abstract: To solve the limitations of traditional surcharge prepressing—including low efficiency, high safety risk, and imprecise load control—during the construction of 0^# and 1^# block scaffolds for continuous beam bridges, it systematically investigated the application of steel strand prepressing technology, with the Nankuo bridge of the Ruili-Menglian Expressway as the engineering case. First, the mechanical mechanism and standardized process flow of the technology were elaborated. Subsequently, a numerical model of the scaffold system was established by finite element software to analyze its mechanical behavior and deformation characteristics under concrete loads. Through on-site implementation of graded synchronous tension prepressing based on the reaction system for steel strands, the safety of the support structure was verified, and its elastic deformation law was accurately obtained. Results indicated that steel strand prepressing exhibited distinct advantages: precise load application, high operational efficiency, and enhanced safety. It shortened the prepressing cycle by over 50% and reduced comprehensive costs by approximately 30%.