Abstract: During the 14th Five-Year Plan period, education will enter a stage of all-round high-quality development. In terms of how to cultivate and practice the values of innovation and entrepreneurship such as dedication and cooperation, some college students’ enthusiasm for innovation and entrepreneurship is not high, but their expectations are too high. Higher vocational college should always adhere to moral education, and actively promote the reform based on accurately grasping the connotation of innovation and entrepreneurship. The efforts will be made to develop subject for innovation and entrepreneurship, speed up the integration of innovation and entrepreneurship education with ideological and political education and professional education, and improve services for innovation and entrepreneurship. It will constantly upgrade the innovation and entrepreneurship ecology based on the school, continuously improve the innovation and entrepreneurship ability of college students, promote their all-round development, and transport more highquality technical talents for the comprehensive construction of a modern socialist country.